艾美捷Ansamitocin P3安絲菌素P3解決方案
Ansamitocin P3通過結(jié)合微管蛋白誘導(dǎo)微管解聚;它具有免疫調(diào)節(jié)和抗癌活性。安薩霉素P3增加T細(xì)胞信號(hào)傳導(dǎo)和抗原攝取，并降低體內(nèi)調(diào)節(jié)性T細(xì)胞水平。
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艾美捷Ansamitocin P3?#LKT-A5472-5mg相關(guān)信息：
cas#：66547-09-9
純度：≥70%
公式：C32H43CIN2O9
配方重量：635.14
溶解度：10毫米二甲基二甲基苯甲酸
儲(chǔ)存溫度：-20°C
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Description
Ansamitocin P3 induces microtubule depolymerization by binding tubulin; it exhibits immunomodulatory and anticancer activities. Ansamitocin P3 increases T cell signaling and antigen uptake and decreases regulatory T cell levels in vivo.
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Product Info
Cas No.?66547-09-9
Purity?≥70%
Formula?C32H43CIN2O9
Formula Wt.?635.14
Solubility?10mM DMSO
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Ansamitocin P3文獻(xiàn)參考：
Martin K, Müller P, Schreiner J, et al. The microtubule-depolymerizing agent ansamitocin P3 programs dendritic cells toward enhanced anti-tumor immunity. Cancer Immunol Immunother. 2014 Sep;63(9):925-38. PMID: 24906866.
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Venghateri JB, Gupta TK, Verma PJ, et al. Ansamitocin P3 depolymerizes microtubules and induces apoptosis by binding to tubulin at the vinblastine site. PLoS One. 2013 Oct 4;8(10):e75182. PMID: 24124473.
