《急診每日一題》正確計(jì)算組織纖溶酶原聚合物（TPA）劑量重要性2021年4月
Question 問(wèn)題：
Dosing of alteplase (TPA) for Acute Ischemic Stroke is complex and has been associated with error resulting in an increased rate of hemorrhagic conversions. How often is TPA administered incorrectly?
組織纖溶酶原聚合物（TPA）劑量計(jì)算是復(fù)雜的，常出現(xiàn)錯(cuò)誤，使出血率增加。不正確給予TPA頻率是什么？
Answer 答案：
19.8% patients had an error associated with TPA administration. More patients who had an error with alteplase administration (12.7%) experienced a hemorrhagic conversion compared to those with no error in administration (7.2%).
19.8%患者出現(xiàn)與TPA給藥相關(guān)的錯(cuò)誤。與正確給予TPA相比（7.2%），更多TPA給藥錯(cuò)誤患者繼發(fā)出血（12.7%）。
參考文獻(xiàn)：
?Dancsecs KA, et al. Am J Emerg Med. 2021 Mar 15;47:90-94
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