DBCO-PEG-Folate二苯基環(huán)辛炔聚乙二醇葉酸

外觀：固體或液體，取決于分子量大小。

PEG可選分子量: 2000,3400，5000

溶解度: 溶于DMSO,DMF,DCM，溶于水。

純度：>95%

保存：-20℃，長期保存，避光，干燥

產(chǎn)品描述：DBCO PEG Folic acid, also called DBCO PEG folate, is one of Nanocs' folic acid PEG derivatives that can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG folate derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. Folic acid, is also known as vitamin M, vitamin B9 or pteroyl-L-glutamic acid. Folic acid is an essential bioactive molecule for numerous biological functions. It participates in the synthesis, repairing and methylation of DNA as well as to act as a cofactor in many biological reactions. DBCO functional folic acid can be easily attached to azide functionalized molecules, particles or solid surfaces.

Copper-free Click Reaction Procedures:

Prepare the azide-containing sample in reaction buffer. Add DBCO conjugate to azide containing sample. Recommendation: Add 1 mole equivalent of limiting reagent to 1.5-3.0 mole equivalents of highest abundance reagent. Incubate the reaction at room temperature for 2-4 hours or 2-12 hours at 4 degree celcius. The reaction is now ready for purification.

結(jié)構(gòu)式：?

供應(yīng)商：杭州新喬生物科技有限公司

杭州新喬生物科技有限公司是國內(nèi)的PEG衍生試劑供應(yīng)商，我公司可以提供各種高分子PEG衍生物，分子量從1000-20000不等，涉及甲氧基PEG|氨基PEG|羧基PEG|巰基PEG|疊氮PEG|八臂PEG|四臂PEG|活性酯PEG |馬來酰亞胺PEG|熒光素PEG|羅丹明PEG|丙烯酸酯PEG|磷脂PEG|琥珀酰亞胺PEG|炔基PEG|羥基PEG|硅烷PEG等基團，同時我公司新推出了單分散的小分子量PEG/PEO衍生物，PEG/PEO的重復(fù)單元從2個-24個不等，產(chǎn)品純度高達98%以上。