Cecropin A (1-7)-Melittin A (2-9) amide, also referred to as CAMEL0, is a synthetic hybrid peptide that is composed of portions of the naturally occurring antibiotic peptide cecropin A and melittin. CAMEL0 shows a better antimicrobial activity than the native molecules, but lacks the hemolytic properties of melittin. Studies revealed that the range of its antimicrobial activity is not only restricted to aerobic microorganisms but also included several gram-negative and gram-positive anaerobic microorganisms. Through its ascertained broad spectrum of antibiotic activity, this hybrid peptide may also represent an effective substitute for ciprofloxacin in the treatment of anthrax infections.

抗菌肽和蜂毒素都具有抗菌效果?？咕腁與蜂毒素A組成而成的雜合肽，具有很強(qiáng)的抑菌活性。抗菌肽中一般含有比較多的堿性氨基酸，因此親水性是比較強(qiáng)的，這部分是抗菌肽的生物活性片段；而蜂毒素獨(dú)特的疏水性以及抗菌活性，可以讓多肽進(jìn)入細(xì)菌質(zhì)膜中，兩種片段結(jié)合，能夠起到消滅細(xì)菌的效果，Cecropin A (1-7)-Melittin A (2-9) amide就是這樣一條具有滅菌效果的雜合肽，由15個氨基酸組合而成

編號: 119043
中文名稱: Cecropin A (1-7)-Melittin A (2-9)，蜂毒素A（2-9
英文名: Cecropin A (1-7)-Melittin A (2-9)
英文同義詞: Cecropin A (1-8)-Melittin A (3-9) amide, Cecropin A-melittin hybrid peptide [CA(1-7)M(2-9)NH2], CAMEL0, CM15
CAS號: 157606-25-2
單字母: H2N-KWKLFKKIGAVLKVL-NH2
三字母: H2N-Lys-Trp-Lys-Leu-Phe-Lys-Lys-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-NH2
氨基酸個數(shù): 15
分子式: C89H152N22O15
平均分子量: 1770.3
精確分子量: 1769.18
等電點(diǎn)(PI): -
pH=7.0時的凈電荷數(shù): 5.97
平均親水性: -0.11428571428571
疏水性值: 0.54
來源: 人工化學(xué)合成，僅限科學(xué)研究使用，不得用于人體。
鹽體系: 可選TFA、HAc、HCl或其它
儲存條件: 負(fù)80℃至負(fù)20℃
標(biāo)簽: 抗菌肽(Antimicrobial Peptides)